|
KMID : 0364519930050010055
|
|
Dong-A Journal Medicine
1993 Volume.5 No. 1 p.55 ~ p.64
|
|
|
Immunohistochemical Studies of the Renal biopsy in Patients with Glomerulonephritis and Hepatitis B Virus Infection
|
|
|
|
|
Abstract
|
|
|
To study hepatitis B virus(HBV) associated glomerulonephritis, 135 patients with glomerulonephritis were evaluated.
@ES The author concluded as follows:
@EN 1) Positive rate of hepatitis B surface antigen(HBsAg) in patient with glomerulonephritis(15.6%) was much higher than that of normal control(5.4%) suggesting that HBV infection is one of the most important of glomerulonephritis in Korea. 2)
There
was no difference in age and renal function between patients with and without HBV infection, but more than 30% of patients with HBV infection accompanied laboratory findings of hepatitis. 3) Minor glomerular abnormality. Membranoproliferative
glomerulonephritis and membranous glomerulonephritis are suggested as the major pathologic findings of HBV associated glomerulonephritis and its prevalences in the same pathologic group were 14.3%, 40%, and 27.3%, respectively. Two cases of
membranoproliferative glomerulonephritis with membranous glomerulonephritis were the unique finding in patients with HBV infection. 4) Direct immunofluorescent study for HBsAg and immunohistochemical study by avidin-biotin-peroxidase complex
method
to
detect HBsAg and hepatitis B core antigen on renal biopsy specimens are inappropriate methods due to lower sensitivity.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|